On
Characteristic Details
Name Aurogra
Active Ingredient Sildenafil Citrate
Common Dosage 100 mg
Indications Erectile Dysfunction
Manufacturer Aurochem Pharmaceuticals
Administration Oral
Availability Prescription
Visit Aurogra

Pharmacokinetics

The pharmacokinetics of Aurogra 100 mg revolves around absorption, distribution, metabolism, and excretion of the active compound, sildenafil citrate. After oral ingestion, it is absorbed swiftly with peak plasma concentrations reached within one hour. The bioavailability of sildenafil stands around 40%, primarily due to the first-pass effect.

Distribution occurs extensively in body tissues, indicating high lipid solubility. The drug binds to plasma proteins at a rate of 96%, contributing to its wide distribution in the system. Sildenafil is metabolized predominantly by hepatic enzymes CYP3A4 and, to a lesser extent, CYP2C9.

Its active metabolites account for approximately 80% of the pharmacologic activity of the ingested dose. The excretion of sildenafil occurs through feces (80%) and urine (13%). Terminal half-life ranges between three to five hours, which is significant for therapeutic efficacy.

Aurogra Use

Aurogra, especially in the 100 mg dose, serves a crucial role in treating erectile dysfunction. Its action facilitates increased blood flow to the penile region, leading to an erection when sexual stimulation is present. The onset of action occurs within 30 to 60 minutes, with a duration of up to four hours.

Patients usually consume the tablet with water, refraining from meals high in fat, which may delay its absorption. The recommendation advises one tablet per day, ensuring adherence to prescribed limits to minimize side effects.

The efficacy of Aurogra hinges on its ability to potentiate the effects of nitric oxide by inhibiting phosphodiesterase type 5 (PDE5). This biochemical cascade maintains cGMP levels, promoting vasodilation in penile blood vessels.

FDA-Approved Indications

The FDA has approved sildenafil citrate, the core ingredient of Aurogra 100 mg, for the treatment of erectile dysfunction. This approval underscores the clinical research supporting its safety and effectiveness. The FDA highlights the therapeutic benefits balanced against the potential for adverse effects.

Patients with specific medical conditions, such as severe cardiovascular disorders, may require tailored prescriptions. Healthcare providers must assess individual health profiles before prescribing Aurogra.

Off-label uses, though not endorsed by the FDA, sometimes include the treatment of pulmonary arterial hypertension. Such applications necessitate expert medical judgment and discretion.

Aurogra Disposal

Proper disposal of Aurogra is vital to prevent accidental exposure and environmental harm. Patients should not dispose of the medication via wastewater or household waste. Instead, they must follow local pharmaceutical disposal regulations.

Pharmacies often offer take-back programs for unused or expired drugs. These initiatives ensure safe and environmentally friendly disposal methods. Patients should consult pharmacists if unsure about disposal practices.

Households must store Aurogra securely, away from children and pets. A locked cabinet prevents accidental ingestion, which can lead to severe health consequences.

Aurogra Signs and Symptoms of Overdose

Recognizing overdose symptoms of Aurogra 100 mg is crucial for timely medical intervention. Excessive intake can result in severe hypotension, prolonged erections, or priapism. Visual disturbances or vision loss also signify overdose.

Symptoms might include dizziness, fainting, or severe headache, necessitating urgent medical evaluation. Immediate medical attention helps prevent irreversible damage.

Healthcare professionals recommend adhering to prescribed doses to avoid the risk of overdose. Patients should maintain open communication with their healthcare provider about any unexpected side effects.

Aurogra Over The Counter

Aurogra’s availability is typically restricted to prescriptions due to its potential side effects and interactions. This ensures proper medical oversight and patient safety. Over-the-counter access is not recommended or legal.

Online sources may claim to offer Aurogra without prescription, posing risks of counterfeit products. Such products may lack efficacy or contain harmful ingredients. Patients must acquire Aurogra through legitimate channels to ensure authenticity.

The role of healthcare providers is crucial in managing erectile dysfunction with Aurogra. They offer guidance on the correct use and monitor any health implications associated with its use.

  • Ensure authenticity through licensed pharmacies.
  • Consult healthcare professionals for guidance.
  • Avoid counterfeit and unregulated products.

The controlled access safeguards patient health and therapeutic outcomes, reinforcing the importance of following medical advice.

Source: